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Brigham and Women's HospitalUnited States of America

nude irani,Dr. Elena Aikawa received her medical degree from the First Moscow Medical Institute, Moscow, Russia in 1984, and obtained a Ph.D. degree in pathology from Institute of Biophysics, Moscow in 1989. She joined Brigham and Women’s Hospital (BWH), Boston in 1991. She is currently an Assistant Professor of Medicine at BWH and Harvard Medical School. She also is a Director of Vascular Biology Program at the Center for Interdisciplinary Sciences and a Principal Investigator at the Center for Excellence in Cardiovascular Research at BWH. Her research focuses on the pathogenesis of valvular heart disease and the mechanisms of cardiovascular calcification. She is a member of the National Institutes of Health (NIH) Working Group on Calcific Aortic Valve Stenosis and of the editorial boards of PLoS ONE, Journal of Extracellular Vesicles, and Arteriosclerosis, Thrombosis, and Vascular Biology. Her work in cardiovascular research is recognized worldwide, as reflected by numerous invited lectures and publications.

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xxsexvideos,Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.

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